Venue: Vivekananda Yuba Bharati Krirangan (Kolkata)

Kick-off: Wednesday, 19:00 (UTC+5:30)

The first of the last eight ties will see India's East Bengal welcoming FC Arkadag of Turkmenistan to the Vivekananda Yuba Bharati Krirangan.

East Bengal, despite a tough Indian Super League season where they currently sit in eighth spot, will consider themselves as the favourites with their passionate fans backing them.

The Indian side topped Group A with seven points while Arkadag won Group B with six points.

An advantage East Bengal will have is that they are midway through their season while Arkadag will still be in pre-season mode. 

Al Arabi SC (KUW) v Al Seeb Club (OMA) 

Venue: Jaber Al-Mubarak Al-Hamad Stadium (Sulaibikhat)

Kick-off: Wednesday, 21:30 (UTC+3)

Al Arabi SC against Al Seeb Club will be a meeting between two teams who are in fine form.

Al Arabi are challenging Kuwait SC for the domestic title while Al Seeb's defence of their Oman Pro League crown is progressing smoothly. 

Leading up to this match, Al Arabi are in a slightly better shape having won 2-1 against Al Nasr this past week while Al Seeb were held to a 1-1 stalemate by Al Khaburah.

Al Seeb, the 2022 AFC Cup™ winners, advanced to the quarter-finals as the Group C winners while Al Arabi booked their place as the best second-placed side from the West Zone after finishing runners-up in Group B.

Venue: Nanzih Football Stadium (Gaoxiong)

Kick-off: Thursday, 19:00 (UTC+8)

Tainan City FC's home ground advantage may not count for much when they welcome Indonesia's Madura United for their first leg tie.

The Chinese Taipei season has not kicked off while Madura United have remained in the thick of action since the conclusion of the AFC Challenge League 2024-2025 group stage. 

The Indonesian side's form, however, has not been good as they are in a relegation battle with the latest 3-1 defeat at the hands of PSM Makassar at the weekend giving head coach Alfredo Vera plenty to do to boost confidence ahead of their continental journey.

Madura United advanced to the knockout stage as the Group E winners while Tainan City finished second in Group D.

Venue: Morodok Techo National Stadium (Phnom Penh)

Kick-off: Thursday, 19:00 (UTC+7)

The top sides of Cambodia and Myanmar will face off on Thursday, with Preah Khan Reach Svay Rieng FC hosting Shan United.

Despite facing a challenge from Phnom Penh Crown FC, Svay Rieng FC are well on course to defend their Cambodian Premier League title as they hold a four-point lead in the Championship Round following Saturday's 5-0 win over Ministry of Interior.

Shan United, meanwhile, have already wrapped up their title-winning campaign, setting the stage for a thrilling showdown.

The Myanmar side topped Group D of the AFC Challenge League while Svay Rieng FC finished second in Group E.