Al Sadd vs Al Nassr

The 2011 AFC Champions League winners Al Sadd go into the second leg against Al Nassr on Monday a goal down, after they let slip a 1-0 lead to lose 2-1 in the first leg in Riyadh.

The Qatari hosts remain the last team from West Asia to lift the Continental title but have a tough test on their hands against the Saudi champions although they do have an away goal advantage.

Al Nassr, meanwhile, are in uncharted territory having never previously gone further than the Round of 16, and that too not since the 2009 edition. They do, though, boast the in-form attacker Giuliano who has scored three times in their three knockout stage matches so far this campaign.

Al Sadd (QAT) vs Al Nassr (KSA)
Venue: Jassim bin Hamad Stadium, Doha
Kick-off: September 16, 18:45 UTC+3

Al Hilal vs Al Ittihad

Something has to give on Tuesday at King Saud University Stadium when fierce rivals Al Hilal and Al Ittihad go into their tie all-square after a goalless draw in front of over 54,000 in the first leg in Jeddah.

The 'Saudi Clasico' failed to catch fire on the pitch last month, despite the passion in the stands, but as a result the match is tantalisingly poised with the first goal set to have a huge impact on the way things play out.

Al Hilal had a flawless home record in the Group Stage, but did lose in Riyadh in the Round of 16 against Al Ittihad's city rivals Al Ahli. By contrast, Al Ittihad's away form has been poor in the Group Stage, but picked up in the Knockout Stage with an impressive 4-3 win at Zobahan, albeit at a neutral venue.

Al Hilal (KSA) vs Al Ittihad (KSA)
Venue: King Saud University Stadium, Riyadh
Kick-off: September 17, 20:00 UTC+3

Urawa Red Diamonds vs Shanghai SIPG

China's Shanghai SIPG showed impressive fortitude to come back from an early two-goal deficit in the first leg as two Hulk penalties in the second half restored parity in an action-packed 2-2 draw at Shanghai Stadium.

However, the two away goals conceded and - perhaps crucially - the yellow card that Hulk picked up that rules him out of Tuesday's meeting at Saitama Stadium could prove key.

Urawa, too, will be without a Brazilian as defender Mauricio Antonio is also suspended but will look to replicate their 2017 title-winning campaign when they defeated Shanghai in the semi-finals.

Urawa Red Diamonds (JPN) vs Shanghai SIPG (CHN)
Venue: Saitama Stadium, Saitama
Kick-off: September 17: 19:30 UTC+9

Kashima Antlers vs Guangzhou Evergrande

A battle between the defending champions and the two-time winners is set to add another chapter into this intriguing encounter when holders Kashima host Guangzhou with the scores level and goalless after an absorbing first leg stalemate in southern China.

Despite a mixed run of form in the Group Stage, Kashima's home results have generally been good in this year's AFC Champions League with three wins from four games, including a 1-0 victory against Sanfrecce Hiroshima in the Round of 16.

Guangzhou, on the other hand, have yet to win a game away from home in the 2019 competition. Nevertheless, they were still able to defeat Shandong Luneng in the Round of 16 via a penalty shootout despite losing 3-2 in Jinan.

And any kind of score draw at Kashima Soccer Stadium would also be enough for Fabio Cannavaro's men due to the away goal rule.

Kashima Antlers (JPN) vs Guangzhou Evergrande (CHN)
Venue: Kashima Soccer Stadium, Kashima
Kick-off: September 18, 19:00 UTC+9