The loss against UAE's Al Ain FC equalled Al Nassr's heaviest margin of defeat on the continental stage and it would have left them hurting.

Seeking to lift the coveted continental trophy for the first time, the defeat was made worse by the fact that they are playing catch-up in the defence of their Saudi Pro League title.

Still, the quality Al Nassr have at their disposal means a bounce back is certainly possible and Cristiano Ronaldo and his teammates will be determined to show the opening defeat was a mere blip.

Neftchi, however, will have a swagger in their step as they seek victory against one of the continent's biggest clubs.

The Uzbekistan side edged Air Force SC of Iraq 1-0 in their opening tie and will not hold back against Al Nassr.