Persepolis came into the tie desperate to get their campaign back on track but it was the home side who threatened first with Boualem Khoukhi sending his free-kick over the bar in the fourth minute.

Persepolis squandered a chance moments later, Lucas Joao squaring the ball for Omid Alishah, whose effort from above the area was easily dealt with by Al Sadd keeper Meshaal Barsham.

A stray back pass from Cristo Gonzalez almost caught Al Sadd off guard in the 10th minute with Vahid Amiri pouncing on the chance, only for Masoud Rigi to shoot just over the bar from distance.

Al Sadd went close in the 17th minute when Akram Afif fed Guilherme off a short corner, whose deflected low effort needed intervention from Persepolis keeper Alexis Guendouz.

Persepolis almost took the lead in the 37th minute when Omid Alishah intercepted Tarek Salman’s backpass, producing a save from Barsham, before Rigi’s follow-up was cleared off the line by Guilherme.

However, it was Al Sadd who broke the deadlock in first half stoppage time with Uribe turning the ball into the back of the net from inside a packed six-yard-box off Afif’s corner.

Al Sadd almost doubled their advantage in the 50th minute when Alishah sent a delightful ball through for Afif, whose run was cut short by an alert Guendouz.

Persepolis threatened six minutes later with Soheil Sahraei angling his headed attempt over the bar, while Joao’s low effort was easily dealt with by Barsham.

Barsham was kept busy, denying Soroush Rafiei’s long-range effort in the 68th minute before foiling Isa Alekasir’s header in the 88th minute, with Alishah rattling the crossbar in the closing stages as Al Sadd held on to seal the second win of their campaign.

Persepolis will look to revive their campaign when they meet Al Gharafa of Qatar on 4 November, while Al Sadd take on Saudi Arabia’s Al Wasl.