AFC Champions League Elite
Both have endured slow starts, with only a point to their names and defeat could have serious repercussions on their knockout stage hopes.
Al Shorta will hope home ground advantage can help them get back on track after suffering a 5-0 defeat to Saudi Arabia's Al Hilal SFC on Matchday Two.
The reverse came after having opened their campaign with a commendable draw against Al Nassr Club and the Iraqi side will be desperate to rediscover their form.
Preview: Matchday Three | AFC Champions League Elite™
Pakhtakor have also found the going tough with their only point coming from the 1-1 draw with Islamic Republic of Iran's Persepolis FC on Matchday two.
The Uzbekistan champions will be meeting Al Shorta for the first time but will go into the tie having not tasted defeat in their last three away matches on the continental stage.
Al Shorta (IRQ) v Pakhtakor (UZB)
Venue: Karbala International Stadium (Karbala)
Kick-off: Monday, 19:00 (UTC+3)
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