AFC Champions League Elite
They will, however, have to brush off their 3-0 defeat to Zob Ahan in the Iran Pro League on Friday while Al Nassr will head into the tie with a spring in their step after edging Al Shabab in their Saudi Pro League encounter.
Having opened their continental campaign with an impressive 3-0 defeat of Qatar's Al Gharafa, Esteghlal found themselves on the receiving end of a 2-0 loss to Al Sadd SC two weeks ago.
While the head-to-head between the two sides is one win each, three of their previous six meetings with teams from Saudi Arabia have ended in defeat.
Preview: Matchday Three | AFC Champions League Elite™
Al Nassr, meanwhile, have discovered their form after a slow start and look well placed to challenge for honours on the domestic and continental fronts.
A 2-1 win against Al Rayyan last time out took them to four points and having not lost in their previous nine meetings with Iranian clubs, they will be confident of another three points on Tuesday.
Esteghlal FC (IRN) v Al Nassr Club (KSA)
Venue: Rashid Stadium, Dubai
Kick-off: Tuesday, 20:00 (UTC+4)
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