AFC Champions League Elite
Both are former continental champions but Qatar's Al Sadd have only beaten Al Hilal of Saudi Arabia once in their four previous meetings in the knockout stage.
Seeking a fifth continental title, Al Hilal will go into the tie unbeaten in each of their last seven games played against teams from Qatar (W6 D1), their longest such streak against Qatari sides in the competition.
They will be confident of their chances after finishing top of the West Zone League Stage, which included cruising to a 3-1 win against Al Sadd.
#ACLElite - Preview: Round of 16 (West)
Al Sadd, on the other hand, qualified for the Round of 16 after finishing eighth, pipping UAE's Sharjah FC on goal difference after both teams finished on eight points.
They will, however, have a spring in their step as they will retain the Qatar Stars League title should Al Shamal fail to defeat Qatar SC on Monday.
They will have to be mindful of their recent record against teams from Saudi Arabia, having lost their last four games.
Al Hilal SFC (KSA) v Al Sadd SC (QAT)
Venue: Prince Abdullah Al Faisal Sports City Stadium (Jeddah)
Kick-off: Monday, 21:00 (UTC+3)
Venue: Prince Abdullah Al Faisal Sports City Stadium (Jeddah)
Kick-off: Monday, 21:00 (UTC+3)
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