AFC Champions League Two
The Saudi Arabian side had to settle for a 2-2 draw after twice taking the lead against Qatar's Al Wakrah in last week's first leg.
Despite having to settle for a stalemate, Al Taawoun will be confident of completing their task at home.
They will go into the tie on a high after edging Al Khaleej 1-0 in a Saudi Pro League tie on Friday, which took them up to 29 points.
#ACLTwo - Preview: Round of 16 (Return Leg)
Al Wakrah will not be lacking confidence either after their fighting performance against one of the tournament favourites.
The Qatari side will feel they have the quality to go one better, having actually dominated the first leg with five shots on target to Al Taawoun's two.
Al Taawoun FC (KSA) v Al Wakrah SC (QAT)
Venue: Wolves Park Stadium (Buraidah)
Kick-off: Wednesday, 21:00 (UTC+3)
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